Brand name: Saffr'Inside™ Saffron
A patented, scientifically researched saffron extract that has been shown to cause a 60% decrease in overall stress levels, with effects being noticed in as little as 5 days. Saffron is a popular spice, which when not used in cooking, can be used for its sleep promoting properties due to the active ingredient safranal. Saffron has shown to be effective in improving insomnia severity as well as the ease of getting to sleep, sleep duration and overall sleep quality.
- Poor Sleep Quality
- Difficulty Falling Asleep
- Low Mood
Saffron is a well-known spice that is commonly utilised for its fragrance and richness in colour. It is the dried stigma of the flower that grows from the Crocus sativus plant and has been widely used in traditional medicine for its therapeutic properties and health benefits.
It contains active compounds, such as safranal, which can have sleep-promoting properties. In fact, safranal has been found to reduce levels of cortisol by up to 44%, which can assist in reducing feelings of stress around bedtime. Saffron extract and its active compounds can also modulate the effects of serotonin, dopamine, norepinephrine, glutamate and GABA-A neurotransmitter which can have an impact on mood, stress, calmness and sleeping ability.
This stress-relieving ingredient, therefore, has therapeutic benefits that can help those struggling with sleep. It has shown to be helpful in improving insomnia severity, as well as improving the duration of non-restorative sleep (sleep which is usually characterised as not sufficiently refreshing or restorative). It is also effective in improving the ease of getting to sleep, sleep duration and overall sleep quality.
Saffron also has the ability to improve stress levels, which can otherwise prevent or impact sleep. Studies found that the consumption of saffron reduced undesirable changes in heart rate which are usually caused by stress.
Two Islands Nightcap contains a specific saffron extract, Safr'Inside™️, in a researched dose, which has been shown to cause a 60% decrease in overall stress levels, with effects being noticed in as little as 5 days.
Due to its extraction process Safr'Inside™️ in particular is the only encapsulated saffron extract on the market. This makes it 8 to 10 times richer in safranal, saffron’s main active compound, than other extracts, guaranteeing the effectiveness of the ingredient.
Safr'Inside™️ Saffron has been the subject of several proprietary studies including a clinical study assessing both chronic and acute efficacy (after only 30min), an in-vivo study showing the direct action of safranal on serotonin, and an open trial under medical supervision that demonstrated that 8 out of 10 consumers are satisfied by Safr’Inside™️ supplementation (and so much more).
Research and studies
We're led by an evidence-based approach, where each product – and every ingredient – has a purpose. As the science of nutrition evolves, we're constantly learning too.
Journal of Pharmacy and BioAllied Sciences
Saffron (Crocus sativus L.): as an antidepressant
Effects of saffron extract on sleep quality: a randomized double-blind controlled clinical trial
Journal of Clinical Sleep Medicine
Effects of saffron on sleep quality in healthy adults with self-reported poor sleep: a randomized, double-blind, placebo-controlled trial
Frontiers in Nutrition
Effects of saffron extract supplementation on mood, well-being, and response to a psychosocial stressor in healthy adults: a randomized, double-blind, parallel group, clinical trial
Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission